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I employ cutting-edge mass spectrometry methods to study the physical structure and function of bio-molecular machines.

These methods characterize the gas-phase behavior of protein complexes, revealing their structural features and the stoichiometry of post-translational modifications, enzymatic cofactors, and metal ions.

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Mass of the Intact Molecular Machine.Dissociation of the molecule to reveal its components.Fragmentation of each component for confident identification.
  1. Mass of the Intact Molecular Machine.

  2. Dissociation of the molecule to reveal its components.

  3. Fragmentation of each component for confident identification.

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Analyzing Mass Spectra

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